Altered expression of IL-1 β, IL-1RI, IL-1RII, IL-1RA and IL-4 could contribute to anovulation and follicular persistence in cattle

Cystic ovarian disease (COD) is an important cause of infertility in dairy cattle. The main signs of this infertility are ovulation failure and follicular persistence. The aim of this study was to examine the expression of the cytokines IL-1 β, IL-1RI, IL-1RII, IL-1RA and IL-4 in ovarian follicular structures at different times of persistence in a model of follicular persistence induced by prolonged administration of progesterone in dairy cows. Protein expression of IL-1β, IL-1RI, IL-1RII, IL-1RA and IL-4 was evaluated by immunohistoc hemistry.

Source: Theriogenology - January 3, 2018 Category: Genetics & Stem Cells Authors: A.F. Stassi, M.E. Baravalle, E.M. Belotti, A.N. Amweg, E. Angeli, M.M.L. Vel ázquez, F. Rey, N.R. Salvetti, H.H. Ortega Source Type: research