Native T1 Mapping and Extracellular Volume Mapping for the Assessment of Diffuse Myocardial Fibrosis in Dilated Cardiomyopathy

Conclusions
Native T1 exhibited comparable ability as ECV measurement in the detection and quantification of histological collagen volume fraction, with high reproducibility, and therefore diffuse myocardial fibrosis in DCM may be reliably assessed by native T1 mapping without the administration of gadolinium contrast agent. In addition, cardiac magnetic resonance–derived ECV showed excellent agreement with histological extracellular space.

Source: Journal of the American College of Cardiology: Cardiovascular Imaging - January 1, 2018 Category: Radiology Authors: Nakamori, S., Dohi, K., Ishida, M., Goto, Y., Imanaka-Yoshida, K., Omori, T., Goto, I., Kumagai, N., Fujimoto, N., Ichikawa, Y., Kitagawa, K., Yamada, N., Sakuma, H., Ito, M. Tags: Original Research Source Type: research