CMR-Derived Extracellular Volume Fraction as a Marker for Myocardial Fibrosis: The Importance of Coexisting Myocardial Inflammation

Conclusions
These findings prove the theoretical concept of ECV as an estimate for diffuse myocardial fibrosis, but only in the absence of significant myocardial inflammation. Assuming that various degrees of myocardial inflammation and fibrosis coexist in such a scenario, the measured ECV will reflect a sum of these different pathologies but will not inform solely on the extent of diffuse fibrosis.

Source: Journal of the American College of Cardiology: Cardiovascular Imaging - January 1, 2018 Category: Radiology Authors: Lurz, J. A., Luecke, C., Lang, D., Besler, C., Rommel, K.-P., Klingel, K., Kandolf, R., Adams, V., Schöne, K., Hindricks, G., Schuler, G., Linke, A., Thiele, H., Gutberlet, M., Lurz, P. Tags: Original Research Source Type: research