Risk of High-Risk Human Papillomavirus Infection and Cervical Precancerous Lesions with Past or Current Trichomonas Infection: A Pooled Analysis of 25,054 Women in Rural China

Human papillomavirus (HPV) is a sexually transmitted disease (STD) and persistent high-risk HPV (hr-HPV) infection is needed for cervical cancer [1]. Most HPV infections resolve within two years [2], but differences in immune systems and exogenic factors affect hr-HPV clearance and progression to invasive cancer. Concurrent STD infection, such as with chlamydia trachomatis, may affect host immunity, incurring a subsequently increased risk of hr-HPV persistence and progression to high-grade cervical intraepithelial neoplasia (CIN  + ) [3–6].

Source: Journal of Clinical Virology - December 30, 2017 Category: Virology Authors: Rui-Mei Feng, Margaret Z.Wang, Jennifer S. Smith, Li Dong, Feng Chen, Qin-Jing Pan, Xun Zhang, You-Lin Qiao, Fang-Hui Zhao Source Type: research