Impact of cellular restriction gene (TRIM5 α, BST‐2) polymorphisms on the acquisition of HIV‐1 and disease progression

ConclusionTRIM5α haplotypes and BST‐2 i19 allele may significantly affect the modulation of HIV‐1 acquisition and its progression. TRIM5α rs7127617 CC and BST‐2 Δ19/i19 genotypes in alcohol using HIV patients elevated the risk of HIV disease progression.

Source: The Journal of Gene Medicine - December 1, 2017 Category: Genetics & Stem Cells Authors: HariOm Singh, Dharmesh Samani, Manisha V. Ghate, R.R. Gangakhedkar Tags: RESEARCH ARTICLE Source Type: research