Long ‐term Effects of Neonatal Hyperoxia in Adult Mice

Conclusions. Prolonged neonatal hyperoxia during a critical period of development induces irreversible lung damage and pulmonary hypertension in adult mice; there were also structural changes in the kidneys and aorta. This could have implications for chronic adult diseases following exposure to high levels of oxygen in the newborn period. This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Far.23766

Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology - December 27, 2017 Category: Molecular Biology Authors: Vasantha HS Kumar, Huamei Wang, Sergei Kishkurno, Babu S Paturi, Lori Nielsen, Rita M Ryan Tags: Full Length Article Source Type: research