NGS typings reveal very high frequencies of particular HLA class II alleles and haplotypes

Abstract
A total of 72 unrelated Mandenka individuals from Eastern Senegal, Niokholo region, were typed using Next Generation Sequencing (library preparation with the Holotype HLA X2 and MIA FORA NGS HLA Typing kits, sequencing with Illumina MiSeq, and bio‐informatic processing with HLA Twin v1.1.1 (Omixon) and MIA FORA NGS software) and yielded reliable genotypes for 8 HLA loci, namely A, B, C, DRB1, DQA1, DQB1, DPA1 and DPB1.

Source: Tissue Antigens - December 27, 2017 Category: Allergy & Immunology Authors: T. Goeury, L. E. Creary, M. A. Fernandez ‐Vina, J.‐M. Tiercy, J. M. Nunes, A. Sanchez‐Mazas Tags: Population Report Source Type: research