Development of a new enzyme immunoassay for improved detection of rotavirus in fecal specimens of vaccinated infants

Group A rotavirus (RVA) is the most common cause of acute viral gastroenteritis in infants and young children and causes approximately 215,000 deaths globally [1,2]. Nearly all children are infected with rotavirus at least once by the age of five years. In the United States, prior to the introduction of rotavirus vaccine, rotavirus gastroenteritis resulted in an estimated 55,000 –70,000 hospitalizations in children less than 5 years of age per year [3,4]. Loss of parental time from work, in caring for ill children, has been estimated millions of dollars per year [5].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research