Pharmacokinetics and pharmacodynamics of canagliflozin in pediatric patients with type 2 diabetes

ConclusionsIn pediatric T2D patients, canagliflozin 100 and 300 mg had PK and PD characteristics similar to those in adults with T2D, which is likely due to the relative maturity and increased body weight of youth affected with this disorder.

Source: Pediatric Diabetes - December 22, 2017 Category: Endocrinology Authors: William V Tamborlane, David Polidori, Domenick Argenti, Nicholas A Di Prospero Tags: ORIGINAL ARTICLE Source Type: research