The inhibitory effects of capillarisin on cell proliferation and invasion of prostate carcinoma cells

ConclusionsOur data indicate that Cap blocked cell growth by modulation of p21, p27 and cyclins. The inhibitory effects of Cap on survivin, MMP‐2, MMP‐9 and STAT3 activation may account for the suppression of invasion in prostate carcinoma cells. Our data suggest that Cap might be a therapeutic agent in treating advanced prostate cancer with constitutive STAT3 or IL‐6‐inducible STAT3 activation.

Source: Cell Proliferation - December 1, 2017 Category: Cytology Authors: Ke ‐Hung Tsui, Ying‐Ling Chang, Pei‐Shan Yang, Chen‐Pang Hou, Yu‐Hsiang Lin, Bing‐Wei Lin, Tsui‐Hsia Feng, Horng‐Heng Juang Tags: ORIGINAL ARTICLE Source Type: research