Increased proportions of B cells with spontaneous production of interleukin ‐10 in HIV‐infected individuals are normalized during combination antiretroviral therapy: a longitudinal study

In conclusion, progressors had elevated B10‐cell proportions, while viremic controllers displayed normal proportions. After initiation of cART, the B10‐cell proportion decreased. This could limit B10‐cell‐mediated suppression of specific CD8+ T‐cell responses.

Source: APMIS - December 21, 2017 Category: Research Authors: Camilla Sambleben, Andreas Dehlb æk Knudsen, Hans J. Hartling, Claus H. Nielsen, Susanne D. Nielsen Tags: Original Article Source Type: research