From network to phenotype: the dynamic wiring of an Arabidopsis transcriptional network induced by osmotic stress

This study resulted in the identification of a core network, composed of ERF6, ERF8, ERF9, ERF59, and ERF98, which is responsible for most transcriptional connections. The analyses highlight the biological function of this core network in environmental adaptation and its redundancy. Finally, a phenotypic analysis of loss-of-function and gain-of-function lines of the transcription factors established multiple connections between the stress-responsive network and leaf growth.

Source: Molecular Systems Biology - December 21, 2017 Category: Molecular Biology Authors: Van den Broeck, L., Dubois, M., Vermeersch, M., Storme, V., Matsui, M., Inze, D. Tags: Genome-Scale & Integrative Biology, Plant Biology, Transcription Articles Source Type: research