Mediterranean Tomato ‐Based Sofrito Sauce Improves Fibroblast Growth Factor 21 (FGF21) Signaling in White Adipose Tissue of Obese ZUCKER Rats

Conclusions: A sofrito‐supplemented diet improves insulin and FGF21 sensitivity in OZR, explaining part of sofrito’s healthy effects on glucose metabolism. In addition, induction of UCP1 and the unchanged body weight despite the hyperphagic behavior of the sofrito‐fed rats suggests that the increase in FGF21 signaling correlates with an increase in energy expenditure (EE). Further studies in humans may help to understand whether sofrito consumption increases the EE in obese individuals.This article is protected by copyright. All rights reserved

Source: Nahrung / Food - December 21, 2017 Category: Nutrition Authors: Viviana Sandoval, Rosal ía Rodríguez‐Rodríguez, Úrsula Martínez‐Garza, Cristina Rosell‐Cardona, Rosa Lamuela‐Raventós, Pedro F. Marrero, Diego Haro, Joana Relat Tags: Food & Function Source Type: research