[Comment] Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?

Tuberculous meningitis, a severe manifestation of extra-pulmonary tuberculosis,1,2 has a mortality of more than 60% in HIV-infected people,3 with a 54% risk of chronic neurological complications in those who survive.2 Rapid diagnosis and early initiation of treatment are needed to improve prognosis and minimise debilitating sequelae.2 However, diagnosis is difficult, because cerebrospinal fluid typically contains few Mycobacterium tuberculosis bacilli and large sample volumes cannot always be obtained.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Comment Source Type: research