Thymidine kinase 1 silencing retards proliferative activity of pancreatic cancer cell via E2F1 ‐TK1‐P21 axis

ConclusionsThe results suggested that TK1 might be involved in the development and progression of PDAC by regulating cell proliferation and show that TK1 may work as a promising therapeutic target in patients with PDAC.

Source: Cell Proliferation - December 20, 2017 Category: Cytology Authors: Xiaole Zhu, Chenyuan Shi, Yunpeng Peng, Lingdi Yin, Min Tu, Qiuyang Chen, Chaoqun Hou, Qiang Li, Yi Miao Tags: ORIGINAL ARTICLE Source Type: research