Sphingolipid metabolism in cancer signalling and therapy

Nature Reviews Cancer 18, 33 (2018). doi:10.1038/nrc.2017.96 Author: Besim Ogretmen Sphingolipids, including the two central bioactive lipids ceramide and sphingosine-1-phosphate (S1P), have opposing roles in regulating cancer cell death and survival, respectively, and there have been exciting developments in understanding how sphingolipid metabolism and signalling regulate these processes in response to anticancer therapy. Recent studies
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research