An evolutionary perspective on field cancerization

Nature Reviews Cancer 18, 19 (2018). doi:10.1038/nrc.2017.102 Authors: Kit Curtius, Nicholas A. Wright & Trevor A. Graham Tumorigenesis begins long before the growth of a clinically detectable lesion and, indeed, even before any of the usual morphological correlates of pre-malignancy are recognizable. Field cancerization, which is the replacement of the normal cell population by a cancer-primed cell population that may show no
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research