Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia

Conclusions: Our findings suggest a contribution of CCL3 and P2X7Rs in the SDH to paclitaxel-induced allodynia and may provide new therapeutic targets for paclitaxel-induced painful neuropathy.

http://www.molecularpain.com/content/10/1/53

Source: Molecular Pain - August 15, 2014 Category: Molecular Biology Authors: Ryutaro Ochi-ishiKenichiro NagataTomoyuki InoueHidetoshi Tozaki-SaitohMakoto TsudaKazuhide Inoue Source Type: research