Marked efficacy of combined three ‐drug therapy (Sodium Valproate, Topiramate and Stiripentol) in a patient with Dravet syndrome

We present a case of DS, in which treatment with CLB could not be continued because of the appearance of adverse reactions to it. Replacement with topiramate (TPM) proved to be markedly effective. What is new and conclusionIt is suggested that combination therapy with VPA, TPM and STP is for DS epilepsy. In drug therapy for patients with Deavet syndrome, combination therapy of Valproate, Clobazam and Stiripentol is recommended. In this case, combination therapy using Topiramate instead of Clobazam, it was effective for epileptic seizures.
Source: Journal of Clinical Pharmacy and Therapeutics - Category: Drugs & Pharmacology Authors: Tags: CASE REPORT Source Type: research