Time-to-Effect-Based Dosing Strategy for Cryoballoon Ablation in Patients With Paroxysmal Atrial Fibrillation: Results of the plusONE Multicenter Randomized Controlled Noninferiority Trial [Original Articles]
Conclusions
The new time-to-effect–based cryotherapy dosage protocol led to shorter cryotherapy and procedure times, with equal safety, and similar acute and 1-year follow-up results, compared with the conventional approach.
Clinical Trial Registration
URL: https://clinicaltrials.gov. Unique identifier: NCT02789358.
Source: Circulation: Arrhythmia and Electrophysiology - Category: Cardiology Authors: Ferrero-de-Loma-Osorio, A., Garcia-Fernandez, A., Castillo-Castillo, J., Izquierdo-de-Francisco, M., Ibanez-Criado, A., Moreno-Arribas, J., Martinez, A., Bertomeu-Gonzalez, V., Lopez-Mases, P., Ajo-Ferrer, M., Nunez, C., Bondanza-Saavedra, L., Sanchez-Gom Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Atrial Fibrillation Original Articles Source Type: research
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