Benefit of Switching Dual Antiplatelet Therapy After Acute Coronary Syndrome According to On-Treatment Platelet Reactivity: The TOPIC-VASP Pre-Specified Analysis of the TOPIC Randomized Study

Conclusions
Switched DAPT was superior regardless of initial platelet reactivity but the benefit was greater in LTPR patients. Indeed, the switched strategy was highly effective in this group, which had impaired prognosis with unchanged DAPT but similar prognosis after switching.

Source: Journal of the American College of Cardiology: Cardiovascular Interventions - December 18, 2017 Category: Cardiology Authors: Deharo, P., Quilici, J., Camoin-Jau, L., Johnson, T. W., Bassez, C., Bonnet, G., Fernandez, M., Ibrahim, M., Suchon, P., Verdier, V., Fourcade, L., Morange, P. E., Bonnet, J. L., Alessi, M. C., Cuisset, T. Tags: Focus on Acute Coronary Syndromes Source Type: research