Treatment outcomes of macrolide-susceptible Mycobacterium abscessus lung disease

Mycobacterium abscessus lung disease is difficult to treat due to inducible resistance to macrolides. However, 15% –20% of isolates are macrolide susceptible. In 14 patients with macrolide-susceptible M. abscessus lung disease, all isolates had nonfunctional erm(41) gene, and sputum culture conversion rate was achieved in 93% (13/14) following antibiotic therapy.

Source: Diagnostic Microbiology and Infectious Disease - December 16, 2017 Category: Microbiology Authors: Hayoung Choi, Byung Woo Jhun, Su-Young Kim, Dae Hun Kim, Hyun Lee, Kyeongman Jeon, O Jung Kwon, Hee Jae Huh, Chang-Seok Ki, Nam Yong Lee, Sung Jae Shin, Charles L. Daley, Won-Jung Koh Tags: Note Source Type: research