Hemodynamics of Fontan Failure: The Role of Pulmonary Vascular Disease [Original Articles]

Conclusions
When coupled with low cardiac index, even mild elevations in PVRI identify patients at high risk of Fontan failure. This suggests that pulmonary vascular disease is a key mechanism underlying Fontan failure and supports further studies to understand the pathophysiology and target treatments to pulmonary vascular tone in this population.

Source: Circulation: Heart Failure - December 15, 2017 Category: Cardiology Authors: Egbe, A. C., Connolly, H. M., Miranda, W. R., Ammash, N. M., Hagler, D. J., Veldtman, G. R., Borlaug, B. A. Tags: Congenital Heart Disease Original Articles Source Type: research