Topical Cidofovir for Treatment-Refractory Ocular Surface Squamous Neoplasia

Ocular surface squamous neoplasia (OSSN) is defined as a group of dysplastic, preinvasive, and malignant squamous lesions involving the cornea and conjunctiva. Management of OSSN varies, and typically is governed by lesion size, distribution, and pathologic severity. Treatment incorporates surgical excision with adjuvant cryotherapy to margins, topical chemotherapy, or both, the latter commonly with mitomycin C and 5-fluorouracil.1 More recently, the application of topical interferon alfa-2b has been used successfully for treating OSSN.

Source: Ophthalmology - December 15, 2017 Category: Opthalmology Authors: Matthew H. Ip, C.R. Robert George, Zin Naing, Elliot M. Perlman, William Rawlinson, Minas T. Coroneo Tags: Reports Source Type: research