Altered Regional and Integrated Resting-state Brain Activity in General Social Anxiety Disorder Patients before and after Group Cognitive Behavior Therapy

We aimed to investigate the recovery neuromechanism underlying the treatment efficacy in generalized social anxiety disorder (GSAD). We recruited fifteen patients with GSAD and nineteen healthy control (HC) participants, all of whom underwent a baseline resting-state fMRI scan. The GSAD patients underwent an additional fMRI scan after group cognitive behavior therapy (GCBT). Amplitude of low-frequency fluctuation (ALFF) and degree centrality (DC) measures were used to examine altered regional and integrated spontaneous brain activity in group comparisons.

Source: Psychiatry Research: Neuroimaging - December 15, 2017 Category: Psychiatry Authors: Minlan Yuan, Hongru Zhu, Changjian Qiu, Yajing Meng, Yan Zhang, Zhengjia Ren, Yuchen Li, Cui Yuan, Meng Gao, Su Lui, Qiyong Gong, Wei Zhang Source Type: research