Substance P in dorsal root ganglion neurons in young and adult rats, after nociceptive stimulation during the neonatal period

In conclusion, neonatal noxious stimulation caused a permanent increase in SP‐positive DRG neurons in males that was not observed in females, suggesting that differences in pain processing/responsivity between genders could be related to morphological alterations of the nervous system. This article is protected by copyright. All rights reserved.

Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology - December 15, 2017 Category: Molecular Biology Authors: Ana Leda Bertoncini Sim ões, Greice Anne Rodrigues Silva, Carolina Giorgetto, Elisabete de Cassia do Carmo‐Campos, Fernando José Dias, Valéria Paula Sassoli Fazan Tags: Full Length Article Source Type: research