Effects of endovascular cooling on infarct size in ST ‐segment elevation myocardial infarction: A patient‐level pooled analysis from randomized trials

ConclusionsThe present study, drawn from a patient‐level pooled analysis of six randomized trials of endovascular cooling during primary PCI in STEMI, showed a significant reduction in infarct size in patients with anterior STEMI who were cooled to <35°C at the time of reperfusion. The results support the need for trials in patients with anterior STEMI using more powerful cooling devices to optimize the delivery of hypothermia prior to reperfusion.

Source: Journal of Interventional Cardiology - December 1, 2017 Category: Cardiology Authors: Michael Dae, William O'Neill, Cindy Grines, Simon Dixon, David Erlinge, Marko Noc, Michael Holzer, Anne Dee Tags: RANDOMIZED TRIAL Source Type: research