Familial Aggregation of Aortic Valvular Stenosis: A Nationwide Study of Sibling Risk [Original Articles]

Conclusions—
A sibling history of clinically diagnosed AS was associated with increased risk of AS. Spouses of patients with AS only had a modest risk increase, suggesting that shared adult environmental factors contribute less to the development of AS than genetic factors.

Source: Circulation: Cardiovascular Genetics - December 14, 2017 Category: Cardiology Authors: Martinsson, A., Li, X., Zoller, B., Andell, P., Andersson, C., Sundquist, K., Smith, J. G. Tags: Cardiovascular Disease, Epidemiology, Genetics, Valvular Heart Disease Original Articles Source Type: research