Monitoring of Anti-Xa in Pregnant Patients With Mechanical Prosthetic Valves Receiving Low-Molecular-Weight Heparin: Peak or Trough Levels?
Conclusions:
Anticoagulation with adjusted dose LMWH aimed to achieve guideline-recommended peak levels of anti-Xa for patients with MPHVs is commonly associated with subtherapeutic trough levels. Routine measurement of trough anti-Xa levels is therefore advisable in women with MPHV treated with LMWH during pregnancy to assure adequate level of anticoagulation.
Source: Journal of Cardiovascular Pharmacology and Therapeutics - Category: Cardiology Authors: Goland, S., Schwartzenberg, S., Fan, J., Kozak, N., Khatri, N., Elkayam, U. Tags: Clinical Studies Source Type: research
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