An overview of Type 2 Diabetes and Importance of Vitamin D3-vitamin D receptor interaction in Pancreatic β-cells

One significant health issue that plagues contemporary society is that of Type 2 diabetes (T2D). This disease is characterised by higher-than-average blood glucose levels as a result of a combination of insulin resistance and insufficient insulin secretions from the β-cells of pancreatic islets of Langerhans. Previous developmental research into the pancreas has identified how early precursor genes of pancreatic β-cells, such as Cpal, Ngn3, NeuroD, Ptf1a, and cMyc, play an essential role in the differentiation of these cells.
Source: Journal of Diabetes and Its Complications - Category: Endocrinology Authors: Tags: Review article Source Type: research