Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers [Original Articles]

Conclusions—
The truncation mutations were associated with manifestation of cardiac phenotypes in LMNA-related cardiomyopathy, suggesting that genetic analysis might be useful for diagnosis and risk stratification.

Source: Circulation: Cardiovascular Genetics - December 13, 2017 Category: Cardiology Authors: Nishiuchi, S., Makiyama, T., Aiba, T., Nakajima, K., Hirose, S., Kohjitani, H., Yamamoto, Y., Harita, T., Hayano, M., Wuriyanghai, Y., Chen, J., Sasaki, K., Yagihara, N., Ishikawa, T., Onoue, K., Murakoshi, N., Watanabe, I., Ohkubo, K., Watanabe, H., Ohno Tags: Arrhythmias, Sudden Cardiac Death, Genetic, Association Studies, Cardiomyopathy, Heart Failure Original Articles Source Type: research