Three ‐Component Enantioselective Cyclization Reaction Catalyzed by an Unnatural Amino Acid Derivative

AngewchemThree ‐Component Enantioselective Cyclization Reaction Catalyzed by an Unnatural Amino Acid Derivative: A new diastereo ‐ and enantioselective three‐component cyclization reaction is described. The reaction takes place between a ketone, a carboxylic acid, and a nitroalkene to yield a bicyclic octahydro‐2H‐indol‐2‐one...

Source: Organometallic Current - December 13, 2017 Category: Chemistry Tags: Enantioselective Multicomponent Rxn organocatalysis Source Type: blogs