Widely Applicable Hydrofluorination of Alkenes via Bifunctional Activation of Hydrogen Fluoride

JacsWidely Applicable Hydrofluorination of Alkenes via Bifunctional Activation of Hydrogen Fluoride: Expanding the use of fluorine in pharmaceuticals, agrochemicals and materials requires a widely applicable and more efficient protocol for the preparation of fluorinated compounds. We have developed a new generation nucleophilic fluorination reagent, KHSO4-13HF, HF 68 wt/wt %, that is not only easily handled and inexpensive but also capable of hydrofluorinating diverse, highly functionalized alkenes, including natural products.

Source: Organometallic Current - December 13, 2017 Category: Chemistry Tags: Fluorination Source Type: blogs