Combined Erlotinib and PF ‐03084014 treatment contributes to synthetic lethality in head and neck squamous cell carcinoma

ConclusionsThese results suggested that concomitant inhibition of the Notch1 and EGFR pathways represented a rational strategy for promoting apoptosis in HNSCC and overcoming treatment resistance.

Source: Cell Proliferation - December 1, 2017 Category: Cytology Authors: Yang Zheng, Zhao Wang, Xu Ding, Yibo Dong, Wei Zhang, Wei Zhang, Yi Zhong, Wenyi Gu, Yunong Wu, Xiaomeng Song Tags: ORIGINAL ARTICLE Source Type: research