Fever of Unknown Origin: the Value of FDG-PET/CT

Fever of unknown origin (FUO) is commonly defined as fever higher than 38.3 °C on several occasions during at least 3 weeks with uncertain diagnosis after a number of obligatory investigations. The differential diagnosis of FUO can be subdivided in four categories: infections, malignancies, noninfectious inflammatory diseases, and miscellaneous causes. In most cases of FUO , there is an uncommon presentation of a common disease. FDG-PET/CT is a sensitive diagnostic technique for the evaluation of FUO by facilitating anatomical localization of focally increased FDG uptake, thereby guiding further diagnostic tests to achieve a final diagnosis.

Source: Seminars in Nuclear Medicine - December 8, 2017 Category: Nuclear Medicine Authors: Ilse J.E. Kouijzer, Catharina M. Mulders-Manders, Chantal P. Bleeker-Rovers, Wim J.G. Oyen Source Type: research