Oncogenic DNA viruses found in salivary gland tumors

Salivary gland tumors (SGTs) are rare, extremely complex entities posing a major challenge for both pathologists and clinicians [1,2]. Despite intensive research beginning in the early ’90, the etiology of SGTs is still unclear [3]. Several human DNA viruses, including human papillomaviruses (HPVs), herpes viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV), and polyomaviruses, have been implicated in a wide variety of tumors, and the majority of these can be dete cted in saliva samples [4–7].

Source: Oral Oncology - November 10, 2017 Category: Cancer & Oncology Authors: Alyce A. Chen, Tarik Gheit, Marco Stellin, Valentina Lupato, Giacomo Spinato, Roberto Fuson, Anna Menegaldo, Sandrine Mckay-Chopin, Elisa Dal Cin, Giancarlo Tirelli, Maria Cristina Da Mosto, Massimo Tommasino, Paolo Boscolo-Rizzo Source Type: research