Internal Peptide Late ‐Stage Diversification: Peptide‐Isosteric Triazoles for Primary and Secondary C(sp3)−H Activation

AngewchemInternal Peptide Late ‐Stage Diversification: Peptide‐Isosteric Triazoles for Primary and Secondary C(sp3)−H Activation: Secondary C(sp3) −H arylations were accomplished by palladium catalysis with triazoles as peptide bond isosteres. The unique power of this approach is highlighted by the possibility of achieving secondary...

Source: Organometallic Current - December 8, 2017 Category: Chemistry Tags: Arylation Pd Catalyzed Peptide Modification sp3 C-H Activation Source Type: blogs