Progesterone attenuates hypertension and autoantibody levels to the angiotensin II type 1 receptor in response to elevated cadmium during pregnancy

Preeclampsia is associated with the presence of pathogenic angiotensin-receptor-activating autoantibodies. Cadmium is an increasingly prevalent environmental pollutant that can mimic oestrogens, which may enhance immunoglobulin production. Progesterone exerts opposite effects to oestrogen.

Source: Placenta - December 7, 2017 Category: Reproduction Medicine Authors: Qiong Zhang, Yinping Huang, Keke Zhang, Yan Yan, Jie Wu, Fan Wang, Yuan Zhao, Huifang Xu, Wei Jiang, Danyang Yu, Yongtao Chen, Duyun Ye Source Type: research