Recognition of self-DNA drives cardiac inflammation: why broken hearts fail
Nature Medicine 23, 1400 (2017).
doi:10.1038/nm.4455
Authors: Kory J Lavine & Douglas L Mann
Signals that govern immune cells in the heart remain poorly defined. A new report in mice shows that pathways involved in sensing viruses orchestrate monocyte and macrophage activation through recognition of DNA derived from dying cardiomyocytes following myocardial infarction.
Source: Nature Medicine - Category: General Medicine Authors: Kory J Lavine Douglas L Mann Tags: News and Views Source Type: research