The Role of lnc-DC long non-coding RNA and SOCS1 in the Regulation of STAT3 in Coronary Artery Disease and Type 2 Diabetes Mellitus
Coronary artery disease (CAD) can be classified as an inflammatory disease, which affected by type 2 diabetes mellitus (T2DM). Elevated levels of many inflammatory molecules were found in the serum of patients with CAD. STAT3 molecule as a transcription factor plays an important role in the cytokines expression. Here, we examined the expression levels of STAT3 and its important regulatory genes lnc-DC and SOCS1, in patients with CAD and T2DM.
Source: Journal of Diabetes and Its Complications - Category: Endocrinology Authors: Asieh Alikhah, Majid Pahlevan Kakhki, Amirhossain Ahmadi, Reyhaneh Dehghanzad, Mohammad Ali Boroumand, Mehrdad Behmanesh Source Type: research