Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity

In this study, we reassessed the role of ROS in glucose-induced sensory axon degeneration and analyzed candidate downstream targets, which could represent druggable targets.

Source: Journal of Diabetes and Its Complications - December 6, 2017 Category: Endocrinology Authors: Ashley L. Waldron, Patricia A. Schroder, Kelly L. Bourgon, Jessie K. Bolduc, James L. Miller, Adriana D. Pellegrini, Amanda L. Dubois, Magdalena Blaszkiewicz, Kristy L. Townsend, Sandra Rieger Source Type: research