Higher serotonin transporter availability in early ‐onset obsessive–compulsive disorder patients undergoing escitalopram treatment: A [11C]DASB PET study

ConclusionsThese findings indicate that the earlier the age of onset of OCD, the less serotonergic pathology there is and that this difference remains even after long‐term serotonin reuptake inhibitor treatment. Clinically, it might suggest that nonserotonergic treatments would be a better option for EOCD patients.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fhup.2642

Source: Human Psychopharmacology: Clinical and Experimental - November 1, 2017 Category: Psychiatry Authors: Junhee Lee, Bo ‐Hyung Kim, Euitae Kim, Oliver D. Howes, Kang Ik Kevin Cho, Youngwoo Bryan Yoon, Jun Soo Kwon Tags: SHORT COMMUNICATION Source Type: research