Localization of thrombospondin ‐1 and its receptor CD36 in the ovary of the ostrich (Struthio camelus)

In conclusion, a fine balance between angiogenic and anti‐angiogenic processes assures that a dense net of blood vessels develops during the rapid growth of a selected follicle. Anti‐angiogenic molecules, such as TSP‐1 and its receptor CD36 may, after the oocyte has reached its final size, inhibit further angiogenesis and limit the transport of yolk material to the mature oocyte. By this mechanism, the growth of the megalecithal oocyte during folliculogenesis may cease.
Source: Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C - Category: Veterinary Research Authors: Tags: ORIGINAL ARTICLE Source Type: research