Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging

ConclusionOur findings indicate that increased numbers of small to medium‐sized DRG neurons respond to mechanical stimuli 8 weeks after DMM surgery, suggesting that nociceptors have become sensitized by lowering the response threshold.

Source: Arthritis and Rheumatism - December 1, 2017 Category: Rheumatology Authors: Rachel E. Miller, Yu Shin Kim, Phuong B. Tran, Shingo Ishihara, Xinzhong Dong, Richard J. Miller, Anne ‐Marie Malfait Tags: Original Article Source Type: research