Serum ‐free complete medium, an alternative medium to mimic androgen deprivation in human prostate cancer cell line models

ConclusionsMedia composition contributed to growth differences observed between CaP cells cultured in SFM or CSM. However, the differences in media composition did not impair CaP cell response to T‐stimulated growth, bicalutamide growth inhibition, metabolism of T, or dutasteride efficiency. SFM can be used as a better defined alternative to CSM for androgen deprivation experiments.

Source: The Prostate - December 1, 2017 Category: Urology & Nephrology Authors: Michael V. Fiandalo, John H. Wilton, Krystin M. Mantione, Carol Wrzosek, Kristopher M. Attwood, Yue Wu, James L. Mohler Tags: ORIGINAL ARTICLE Source Type: research