Brief Report: A Novel ELANE Mutation Associated With Inflammatory Arthritis, Defective NETosis, and Recurrent Parvovirus Infection

ConclusionThis is the first report of a human pathogenic ELANE mutation associated with a defect in NETosis and a distinct syndrome of recurrent viral infection and chronic inflammation.

Source: Arthritis and Rheumatism - November 8, 2017 Category: Rheumatology Authors: Uma Thanarajasingam, Mark A. Jensen, Jessica M. Dorschner, Theresa Wampler Muskardin, Yogita Ghodke ‐Puranik, Monica Purmalek, Elias Eliopoulos, Maria I. Zervou, George N. Goulielmos, Matthew Howard, Mariana J. Kaplan, Timothy B. Niewold Tags: Brief Report Source Type: research