Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine

This study demonstrates that MPO gene deletion or supplementation with the natural product taurine, which can scavenge MPO-generated oxidants, can prevent AAA formation, suggesting an attractive potential therapeutic strategy for AAA.

Source: AJP: Heart and Circulatory Physiology - December 1, 2017 Category: Cardiology Authors: Kim, H. W., Blomkalns, A. L., Ogbi, M., Thomas, M., Gavrila, D., Neltner, B. S., Cassis, L. A., Thompson, R. W., Weiss, R. M., Lindower, P. D., Blanco, V. M., McCormick, M. L., Daugherty, A., Fu, X., Hazen, S. L., Stansfield, B. K., Huo, Y., Fulton, D. J. Tags: RESEARCH ARTICLE Source Type: research