Site-selective and stereoselective functionalization of non-activated tertiary C –H bonds

Site-selective and stereoselective functionalization of non-activated tertiary C –H bondsKuangbiao Liao, Thomas C. Pickel, Vyacheslav Boyarskikh, John Bacsa, Djamaladdin G. Musaev + et al.Nature 551, 609 –613 (30 November 2017)doi:10.1038/nature24641The functionalization of specific inert C –H bonds avoids the need for functional groups in organic synthesis and here the challenges of this approach are overcome using a dirhodium catalyst that is capable of C–H bond site-selectivity.

Source: Organometallic Current - November 30, 2017 Category: Chemistry Tags: C-H Functionalization Rh Catalyzed Source Type: blogs