F-actin organizes the nucleus

Nature Cell Biology 19, 1386 (2017).
doi:10.1038/ncb3650

Authors: Henna M. Moore & Maria K. Vartiainen
After mitosis, the nucleus must be rebuilt and chromatin decondensed to permit interphase genomic functions, but decondensation mechanisms are poorly understood. Now, the traditional cytoskeletal protein actin is shown to form transient nuclear filaments that are required for chromatin decondensation and nuclear expansion at mitotic exit.

Source: Nature Cell Biology - November 29, 2017 Category: Cytology Authors: Henna M. Moore Maria K. Vartiainen Tags: News and Views Source Type: research