RNA takes over control of DNA break repair

Nature Cell Biology 19, 1382 (2017). doi:10.1038/ncb3645 Authors: Francesca Storici & Ailone E. Tichon Small RNAs generated at DNA break sites are implicated in mammalian DNA repair. Now, a study shows that following the formation of DNA double-strand breaks, bidirectional transcription events adjacent to the break generate small RNAs that trigger the DNA damage response by local RNA:RNA interactions.
Source: Nature Cell Biology - Category: Cytology Authors: Tags: News and Views Source Type: research