RNA takes over control of DNA break repair
Nature Cell Biology 19, 1382 (2017).
doi:10.1038/ncb3645
Authors: Francesca Storici & Ailone E. Tichon
Small RNAs generated at DNA break sites are implicated in mammalian DNA repair. Now, a study shows that following the formation of DNA double-strand breaks, bidirectional transcription events adjacent to the break generate small RNAs that trigger the DNA damage response by local RNA:RNA interactions.
Source: Nature Cell Biology - Category: Cytology Authors: Francesca Storici Ailone E. Tichon Tags: News and Views Source Type: research